The Effect of Water Extract of Artemisia herba alba Plant on Some Physiological Blood Parameters of Albino rat Males to induce Diabetis
journal of kerbala university,
2014, Volume 10, Issue 2, Pages 282-291
AbstractSeventy five Albino rat Males were randomly divided into five groups (15 animals per group) the first group G1 as control group and it was dosaged daily with a solution of Physiology normal saline for two months and promised to set control as negative, the second group G2 as induced diabetes by injected its by alloxan with 150 mg / kg of body weight under intraperitoneal and promised to set control as positive , while the third , fourth and fifh groups have been induced diabetes before the dosage by ingected with alloxan and dosage orally after month from induced diabetes with aqueous extract of Artemisia herba alba by 500 , 1000 and 1500 mg/kg of body weight per a day for a month , respectively .Blood samples were collected from all groups before induced diabetes, a month after induced diabetes , and after a month of dosing aqueous extract ofArtemisia herba alba for the study of the following parameters : level measurement Blood Hemoglobin (Hb), measure the number of Red blood corpscules count (R.B.C), measuring the total number of White blood cells count (W.B.C) ,and Packed Cell Volume(%PCV) the results showed :
The induced diabetes led to a significant decrease (P<0.05) in the level of Hb, and the number of R.B.C, andPacked Cell Volume(%PCV) with hihg significant (P<0.05) in the number of W.B.C compared to the control group , And get high moral (P<0.05) in the level of Hb and in the number of R.B.C, with hihg non significant (P>0.05) in %PCV and a significant decrease (P<0.05) in the number of W.B.C groups in treatment with aqueous extract of Artemisia herba alba , compared to the infected control group .
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