Effect of Lead acetate on the blood physiological criteria and the level of liver enzymes in male white rats Rattus rattus
journal of kerbala university,
2012, Volume 8, Issue 0, Pages 203-214
AbstractThis study was conducted in the animal house of the Faculty of Medicine / University of Kufa on 60 male rats Rattus rattus weighing 200 g and of two months age in 2009 for the period from 1/7/2009 until 1/1/2010 to know the Lead acetate in some blood physiological criteria and the level of liver enzymes in treated animals .
The results of the current study showed that there was a significant decrease in the concentration of Hemoglobin Hb and the number of Red Blood Corpuscles (RBCs) and the mean of the Packed Cell Volume( PCV) and a significant increase in the total number of white blood cells (WBCs) and the mean of Erythrocytes Sedimentation Rate( ESR).
The results showed significant reductions in the Mean Corpuscular Volume (MCV), Mean Corpuscular Hemoglobin (MCH) ,the Mean Corpuscular Hemoglobin Concentration (MCHC) index , Color Index (CI) and Volume Index (VI), while the results showed significant increases in the level of liver enzymes Alanine amino transaminase ALT and Aspartate amino transaminase AST when compared with the control group and these effects were more pronounced at the doses of 30 mg / kg and 40 mg / kg for the period of 50 days.
- Article View: 148
- PDF Download: 73