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  2. Volume 2, Issue 2
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ISSN: 1813-0410

Volume2, Issue2

BIOLOGICAL ACTIVITY OF SOME NICKEL(II) COMPLEXES

    Zuhoor F. Dawood Adeba Y. Shareef Manal A . Al-Shama

journal of kerbala university, 2006, Volume 2, Issue 2, Pages 86-94

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Abstract

The biological activity of some nickel (II) complexes containing mixed ligands {having the formulaes [Ni2(Sch)2(Py)4(NO3)2](NO3)2 and [Ni2(Sch)2(Py)4(NO3)3]NO3 (where Sch=benzaldehyde semicarbazone - Bsch or 2-fluorobenzaldehyde semicarbazone - Fsch; Py = substituted pyridine: 2-aminopyridine - Py1, 4-aminopyridine – Py2, 2,3-dicarboxypyridine - Py3, 2-amino-3-hydroxypyridine - Py4, 2-amino-4-methylpyridine - Py5 or 3,4-dicarboxypyridine - Py6 )} in dimethylsuphoxide solutions(DMSO) have been evaluated by agar plate diffution technique against five human pathogenic bacterial strains: Bacillus subtilis, Streptococcus pyogenes, Staphylococcus aureus, Pseudomonas aeruginosa and Proteus vulgaris . The complexes were found to have antimicrobial activity on some gram-positive and gram-negative bacteria, in vitro. The effective concentration ranging between 62.5-500 µg/ml. Pseudomonas aeruginosa were the most sensitive bacteria followed by Staphylococcus
Keywords:
    nickel Semicarbazone Substituted pyridine Mixed ligands Biological activity
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(2006). BIOLOGICAL ACTIVITY OF SOME NICKEL(II) COMPLEXES. journal of kerbala university, 2(2), 86-94.
Zuhoor F. Dawood; Adeba Y. Shareef; Manal A . Al-Shama. "BIOLOGICAL ACTIVITY OF SOME NICKEL(II) COMPLEXES". journal of kerbala university, 2, 2, 2006, 86-94.
(2006). 'BIOLOGICAL ACTIVITY OF SOME NICKEL(II) COMPLEXES', journal of kerbala university, 2(2), pp. 86-94.
BIOLOGICAL ACTIVITY OF SOME NICKEL(II) COMPLEXES. journal of kerbala university, 2006; 2(2): 86-94.
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Publisher: Kerbala University

Email:  Journal@uokerbala.edu.iq

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