Study of the immune impact of the cold aqueous extract of Carthamus tinctorius L. plant flowers at Albino rat females Rattus rattus.
journal of kerbala university,
2015, Volume 11, Issue 2, Pages 33-43
AbstractFor the medical importance of the Carthamus tinctorius L. plant and usage it in wide range to treat different pathological states, so the present study was designed to know the effect of the cold aqueous extract of Carthamus tinctorius L. plant flowers on the body , liver weights and the immune system. The study had been carried out in the animal house of the biology department / Faculty of Education for girls, and was included the follow up (60) Abino rat famales at (12) weeks age of Sprage -Dawley breed, were divided into four equal groups, the first was a control group injected with the physiological normal saline (0.9 %) , while the other three groups were injected with 45, 90 and 130 mg / kg concentrations of cold aqueous extract of the plant flowers.The following findings were obtained: a significant decrease (p<0.05) in the body , liver weights and the percentage of neutrophils of treated rats femals with the concentration of 130 mg / kg of cold aqueous extract of the Carthamus tinctorius L. plant flowers when compared with the control group and with two concentrations(45, 90 mg / kg) which did not any notice significant differences between them ,in upon the results were revealed a significant increase (p<0.05)in the the total count of white blood cells at the rat groups which treated with the concentrations(90,130) mg / kg when compared with the control group,so there signifticant differences were showed between the three groups that treated with the plant extract.Also the results pointed to a significant increment (p<0.05) in the total protein and globulin concentrations in the serum and the percentage of lymphocytes in the blood when injection with
the concentration(130 mg /kg) of the extract as compared with the control group as while as with the other concentrations(45, 90 mg /kg) which had not showed any signifticant differences.In related with the albumin concentraction in the serum,it had not revealed a significant difference (p >0.05) when compared the three concentrtions of extract with the control group and with each other.
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