ISSN: 1813-0410

Keywords : DDM


Synthesis, Characterization and Antimicrobial Activity of Schiff Base Complexes of Copper (II), Cobalt (II) and Nickel (II) Derived from 4,4' - Diamino Diphenyl Methane (DDM) and 4,4'-Diamino Diphenyl Ether (DDE) with salicylaldehyde

Amjed A. Ahmed

journal of kerbala university, 2010, Volume 6, Issue 4, Pages 256-271

Tetra dentate N2O2 type complexes of Cu (II), Co (II) and Ni (II) ions have been synthesized using the Schiff bases formed by the condensation of salicylaldehyde (2-hydroxy benzaldehyde) with two diamines, 4,4 - diamino diphenyl methane(DDM) to give Schiff base (L1) and 4,4'-diamino diphenyl ether (DDE) to give Schiff base (L2). Molar conductance , FTIR spectroscopy, UV- visible spectroscopy studies have been carried out to determine the structures of these complexes, from these data it is found that all the complexes posses general stereochemistry [M(L)]2.X,( L= Schiff base (L1 and L2) ; X=Cl4 when M= Cu (II), Co (II) and X=(CH3COO)2 when M= Ni (II), The ratio 2:2 ( M:L) complexes showed square planer geometry around Ni(II ), Co( II ) and Cu(II) ions. FTIR spectra showed that ligands (L1 and L2) is coordinated to the metal ions through imino nitrogen (–CH=N–) and phenolic (–OH) oxygen. The Molar conductance data reveal that all synthesized complexes are electrolyte. Another interesting results of this study is the fact that the molar conductance of Cu (II) complexes of Schiff base (L1 and L2) (L1Cu and L2Cu) are higher than those of Ni(II) and Co (II) complexes with the same ligand, ( L1Ni and L1Co) and ( L2Ni and L2Co) respectively. The Ligands (L1and L2) and their complexes were screened for antimicrobial activity by the well diffusion technique using DMSO as a solvent. The biological activity studies showed that all the prepared complexes are antimicrobially active and showed higher activity than free ligands, the complexes derived from ligand L2 gave higher activity than L1 complexes