ISSN: 1813-0410

Keywords : Sulfa drugs


Synthesis, characterization and biological activity of some sulfadrugs derivatives

Bushra k. Al-Salami; Nahid H. Alhydri; Afrodet A. Salih

journal of kerbala university, Volume 1, Issue 0, Pages 146-153

Sulfamethoxypyridiazine and sulfapyridine have been condensed with selected acyl chloride, namely benzoyl chloride, sebacoyl chloride and terephthayl chloride. The compounds were characterized by FTIR, 1H NMR and elemental analysis. The antibacterial activity of the studied compounds was determined againset several clinical microbial isolates which are; Staphylococcus aureus and E.Coli by using different concentrations of each compound. The results shown the prepared compounds have varying degrees of inhibiting the test microorganisms