ISSN: 1813-0410

Author : Ameer Oda Ismail, Abdul

Anti-tumor Activity Of Virulent Newcastle Virus With Urtica pilulifera On Mammary Adenocarcinoma In mice

Abdul Ameer Oda Ismail

journal of kerbala university, Volume 3, Issue 2, Pages 85-94

The anti-tumor activity of the Virulent Newcastle Virus (VNV) (LD50109) and water extract of Uritica pilulifera leaves (U.P) were evaluated against the murine mammary adenocarcinoma transplanted subcutaneusly in mice . The activity was assessed using growth inhibition of tumor volume, relative tumor volume and histopathological examination. Intratumoral injection of (VNV) and Uritica pilulifera crude extract was given different doses resulted in a prominent suppression of tumor statistically orally withsignificant with 82%,the relative tumor volume was also reduce and the suppression of tumor size in this group more than others. Histopathological examination show massive necrosis associated with fibrosis and lymphocytic with macrophagic infiltration