Author : Hadi Mansoor Al-Saadi, Narjis
Study the obesity effect and its associated diseases on the lipid profile and albumin levels in obese individual
journal of kerbala university,
Volume 5, Issue 3, Pages 80-89
Obesity refers to body mass index (BMI) greater than 30 kg/ m2. This study was conducted on the 44 obese subjects their biomass index over than 30 and 27 non-obese healthy control. Parameter assessed were (BMI) weight in kg / hight2 in meter, lipid profile, and albumin. The results revealed that there are highly significant increase (p<0.001) in concentration of cholesterol, triglycerides, LDL and VLDL and significantly increased (p<0.01) in concentration of HDL comparing with the control. In addition albumin concentration was non significant difference (p>0.05) comparing with the control. The statistical analysis demonstrated that there wasn’t significant difference (p>0.05) in lipid profile and albumin concentration between male and female but there was highly significant increase (p< 0.001) in female BMI comparing with male. When the subjects were classified into two groups depending on associated diseases, the result showed that there was highly significant increased (p<0.0001) in concentration of cholesterol, triglycerides and VLDL in obese subjects with diseases (57%) comparing with healthy obese subjects (43%). Also there was significant increase (p<0.05) in concentration of HDL and albumin in obese subjects with diseases when comparing with healthy obese, Whereas LDL concentration was significantly increased (p<0.01). In contrast when classified the subjects according to their age, group1 (18-40) year and group2 (41-80) year. The results appear that there were no significant differences (p>0.05) in concentration of lipid profile and albumin between these groups. Significant correlations were found between BMI and LDL in obese female (p<0.05) whereas there were significant correlation between BMI and HDL (p<0.01) and significant correlation between BMI with each VLDL and triglycerides (p<0.05) in obese male. In addition there wasn’t significant correlation between age and lipid profile according to Pearson's coefficient.
The objective of this study was to validate the relationship of lipid profile with many diseases, such as diabetes mellitus, atherosclerosis, and coronary heart diseases in obese subjects comparing with healthy non-obese.