ISSN: 1813-0410

Author : H. M, Hamid


Synthesis and Studies The Biological Activity of New Azo Compounds

Zeinab N.M; Hamid H. M; Istabraq M. A

journal of kerbala university, 2011, Volume 7, Issue 1, Pages 75-83

The cyclohexanone was subjected to Hantzsch synthesis by treating with iodine and thiourea to give an intermediate 2-amino-4,5,6,7- tetrahydrobenzothiazole. This was then diazotized and coupled with various phenols and naphtholes derivatives to give a series of new disperse dyes. These azo derivatives were characterized by spectral methods 1HNMR , FT-IR, UV-VIS..
These derivatives were tested against three microorganisms Klebsiella, Pseudomonas aeuroginosa and Escherichia Coli. Some of azo compounds was slightly and non active while azo-2-naphthol was highly acive against all the bacteria species tested.