ISSN: 1813-0410

Author : AbdalnabiJwaiedAbid,

Immunological response of diarrheal patients with determination of mice immunological state against some enteric bacteria


journal of kerbala university, Volume 1, Issue 0, Pages 78-82

Blood and stool cultures of gastrointestinal patients reveals two major types of bacteria , Citrobacterfreunds and Salmonella typhi . Citrobacterfreundiform high rate of these isolates . Somatic and flagellar antigen of S. typhi , outer membrane protein ( OMPs) and lipopolysaccharides (LPS) antigens of C. freundi were isolated .
Antibody and complement components titers show enhancement during early stage of infection . Mice that infected with bacteria reveals enhancement of immunological response represented by increasing of migration inhibition index value ( MIF ) and phagocytosis of infectious agents . Skin test also done for immunized mice with bacterial antigen Group of mice that Immunized with Somatic antigen of Salmonella and group that immunized with OMP of Citrobacter give a positive results for Delayed type hypersensitivity test .