ISSN: 1813-0410

Author : FrialGemeelAbd,

The role of bird thymus extract on some immunological parameters in rabbits vaccinated with killed Salmonella typhi

FrialGemeelAbd; Lubnaabd al- adeemMjeed

journal of kerbala university, Volume 8, Issue 2, Pages 47-52

Three groups of rabbits were used to study the effect of bird thymus extract with protein concentration of 1.5 mg /ml .First group was injected with thymus extract ,second group was injected with thymus extract and killed Salmonella antigen and third group was injected wiN n th killed Salmonella antigen .After the period of immunization schedule was completed ,Blood samples , intestinal and appendix were collected to study some immunological parameters (direct agglutination with Salmonella antigen ,IgM ,IgG concentrations ,LIF ,IFN-ᵞ ,phagocytic activity and delayed type hypersensitivity ).Thymus extract was effect on humoral immunity by increasing the mean of specific titers against Salmonella in second group(533.33 ,53.3, 53.3)while third group were (266.6 ,26.6 ,26.6),the concentrations of immunoglobulin (IgM, IgG)also increased in second group compared with other groups .while in cellular immunity the results were differences between groups .
In this study we confirm, The immunomodulatory effect on previously mention parameters