Author : Abdel mahdi Kassim Altaee, Raeed
Evaluation the analgesic and anti-inflammatory activity of aqueous extracts of Iraqi propolis in male Albino mice
journal of kerbala university,
2014, Volume 10, Issue 0, Pages 1-6
The present study was designed to evaluate the analgesic and anti-inflammatory activity of the aqueous extracts of Iraqi propolis(AEIP) in male mice, AEIP at the doses of 100,200 and 300mg/kg/orally. For the evaluation of analgesic activity hot plate and acetic acid were used, while for anti-inflammatory we using carrageenan to induce paw edema. The results exhibited significant p<0.001 and dose dependent activity compared with the control by increasing in reaction time to thermal stimuli and reduction in abdominal writhing induced by acetic acid, furthermore AEIP was significantly p<0.001 reduced paw edema induced by sub planter injection of carrageenan. In conclusion oral administration of AEIP showed that it has antinociceptive and anti-inflammatory activities .