Author : Oudah Kadhim AL-Shimmary, Fateh
Comparative study by using three different type of Infectious bursal disease vaccine in broiler chicken .
journal of kerbala university,
2014, Volume 10, Issue 1, Pages 16-22
This study was carried out to compare the immunological response produced by using three different types of IBD vaccine .This study was conduct in the Kerbala city by using one hundred and forty broiler chicks of Ross breed were used in this study ,twenty chicks were sacrificed randomly for ELISA test to detect of maternal antibody of IBD at one day of age ,While the other one hundred and twenty chicks were divided in to four equal groups vaccinated by live attenuated vaccine against IBD at 14 days age by drinking water method as followed : Group G1: 30 birds were vaccinated with a hot vaccine live attenuated ((Intervet 228E vaccine)) in the drinking water at, 14 days of age. Group G2: 30 birds were vaccinated with a intermediate plus live attenuated (Ceva IBD-L) in the drinking water at 14 days of age. Group G3: 30 birds were vaccinated with a intermediate live attenuated (Intervet D78 vaccine) in the drinking water at 14 days of age. Group G4: 30 birds were not vaccinated (control). ELISA test were conducted to determine antibody titer at one, 21, 32 days of age for all groups in addition to histology of bursa of fabricious were done in present study. The results showed significant differences at (p<0.01)among vaccinated groups ,the antibody titer was higher in groups vaccinated with intermediate plus and intermediate strain than that virulent strain. And also the results of histological examination of bursa of Fabricius showed that intermediate plus and intermediate strain did not causes harm effects on chicken immune system . This study showed that vaccination by intermediate plus IBD vaccine strain gave a batter immune response and safety than virulent and intermediate vaccine in case of high maternal immunity.