Author : Hamid Ouda, Mazin
journal of kerbala university,
Volume 11, Issue 0, Pages 216-225
This study was performed to determine the effect of Tribulus terrestris in genital male rats treated with amlodipine. Twenty four animals from adult male albino rats were divided into four groups ( six animals per group), the first one is considered as a control group, the second group treated with 0.2 mg/kg of amlodipine , the third group where treated with 5 mg/kg of Tribulus terrestris and the fourth group is the mixed one in which the animals treated with both amlodipine (0.2 mg/kg) and the Tribulus terrestris (5 mg/kg). The experiment lasted for six weeks and then after the animals were sacrificed in order to the study of hormonal and pathological changes.
The results revealed no significant increase in the levels of the testosterone hormone in a group treated with Tribulus terrestris as well as the study showed some histological changes are important for Tribulus terrestris represented with the increase in the development of sperms compared with amlodipine group which showed some negative effects.
The study concluded that there was an effective reproductive efficiency of Tribulus terrestris in spite of the inability of the plant to minimize the negative effects of amlodipine.