Author : A. Ali, Alaa
The Effect of Omega-3 in the Management of Clinical Symptoms and Quality of Life Deterioration in Iraqi Chronic Asthmatic Patients.
journal of kerbala university,
Volume 11, Issue 2, Pages 135-146
Asthma is a chronic inflammatory disorder of the airways in which many cells and cellular elements play a role. In susceptible individuals, this inflammation causes recurrent episodes of coughing (particularly at night or early in the morning), wheezing, breathlessness, and chest tightness.
In secondary care populations up to 50% of patients with asthma have been reported to have clinically significant depressive symptoms and over a third of asthmatic outpatients have been found to have a major depressive episode.
There is some evidence that omega-3 fatty acids are related to mental health, including that they may be useful as an add-on for the treatment of depression associated with bipolar disorder. However, significant benefits due to eicosapentaenoic acid (EPA) supplementation were only seen when treating depressive symptoms and not manic symptoms suggesting a link between omega-3 and depressive mood.
The aim of the present study was to investigate the effect of omega 3 on the management of moderate persistent asthmatic patient who are poorly responded on a combination of inhaled corticosteroids and long acting ß 2 agonists.
Forty five asthmatic patients were included in the study, 21 male and 24 female, who were uncontrolled adequately with inhaled combination of corticosteroids and long acting ß2 agonists. The effect of omega 3 was investigated after 1,2,3 and 4 weeks on symptom frequency, night symptoms and quality of life.
The result of the study evoked a positive effect on all studied parameters that might be agree with old studies and denied with others.
The study concluded that omega 3 might be play an important role in the management of clinical symptoms and quality of life of asthmatic patients.