journal of kerbala university

The study involved twenty healthy adult male rabbit ( Lepus articus) the average weight (1.54 – 1.36) K.g and (6-8) month old. The rabbits were divided in to two groups , the first group was involved (10) rabbit treated by subcutaneous injection (6) ml with Alcoholic extract of Nigella sativa seeds .The second group was control group treated with normal saline solution involved (10) rabbit. The study aimed to determine the effect of Nigella sativa – extracts on level of some enzymes AST , ALT , and blood sugar and level proteins such as total protein , albumin , globulin , and some blood parameters such as red blood cells , white blood cells , Hemoglobin and Biochemical parameters ( Cholesterol , Triglycerides, Low density lipoprotein , Very low density lipoprotein and High density lipoprotein) in this study was found :
Significant increase (P < 0.05) in the mean levels of total protein albumin Red blood cells , white blood cells Hemoglobin high density Lipoprotein , compared with control group. Significant decrease (P < 0.05) in the mean levels of enzymes concentration AST , ALT Blood sugar , cholesterol , Triglycerides , low density lipoprotein , very Low density ,Lipoprotein ,compared with control group.
No significant (P > 0.05) in mean levels of globuline compared with control group.