ISSN: 1813-0410

Author : A. Nasir Al- Amery, Ahmed


In vitro activity of Triazolo[1,5-a] pyrimidine carboxylic acid extracted from microalgae Hapalosiphon welweschii against the protoscolices of hydatid cyst

Amal KH. Khalaf; Ahmed A. Nasir Al- Amery

journal of kerbala university, Volume 10, Issue 3, Pages 328-334

The aim of the present study is testing the activity of Triazolo[1,5-a] pyrimidine carboxylic acid extracted from Hapalosiphon welweschii against the hydatid cyst of Echinococcus granulosus. . the results was found that the compound of the methanol extract of Hapalosiphon welweschii is more active by it is explain in vitro activity against the protoscolices of hydatid cyst where the protoscolices are killed after three days – post treatment in concentrations 300 µg / ml followed by 200 µg / ml that explain activity after five days - post treatment in comparison with the third concentration 100 µgml where revealed low activity with the others. GC- Mass spectrum of the methanol extract has explain presence of the compound Triazolo[1,5-a] pyrimidine carboxylic acid in about 13.28 % from the total composition of methanol extract of microalgae H. welweschii